Details for gene set INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	truncNotch
GeneSet	INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Enrichment Score (ES)	0.7016353
Normalized Enrichment Score (NES)	1.4321809
Nominal p-value	0.046153847
FDR q-value	0.62329286
FWER p-Value	1.0

Fig 1: Enrichment plot: INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS10	2340292	487	2.156	0.3398	Yes
2	RGS19	7050427	1944	1.009	0.4328	Yes
3	RGS3	60670 540736 1340180 1500369 3390735 4010131 4610402 6380114	1960	1.004	0.6025	Yes
4	RGS14	380086	2515	0.760	0.7016	Yes
5	RGS1	4060347 4540181	5036	0.188	0.5981	No
6	GNAQ	430670 4210131 5900736	5095	0.183	0.6261	No
7	RGS9	1050273	6559	0.093	0.5631	No
8	RGS6	6040601	7483	0.062	0.5241	No
9	RGS18	1780019	7550	0.061	0.5308	No
10	RGS11	2360041	7683	0.057	0.5333	No
11	RGS7	3390044	8020	0.049	0.5236	No
12	RGS4	2970711	8235	0.044	0.5195	No
13	RGS13	3780722	8910	0.030	0.4884	No
14	RGS2	1090736	10839	-0.002	0.3851	No
15	RGS16	780091	11252	-0.009	0.3644	No
16	RGS17	1400603	13877	-0.086	0.2380	No
17	RGS20	4540541 4730086	14065	-0.099	0.2447	No

Fig 3: INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING): Random ES distribution
Gene set null distribution of ES for INOH_[NEGATIVE REGULATION OF (G ALPHA S GDP-GTP EXCHANGE SIGNALING)